Welcome to
the CRP Clinic

Renewing Hope, Fulfilling Dreams, Embracing New Life.

We specialise in advanced treatments to address pregnancy loss and fertility challenges.

I'm looking
for help with miscarriages

I need
help to get pregnant

I want to
check on my baby's health

The CRP Clinic was founded by Professor Hassan Shehata, a renowned Consultant Obstetrician and Gynaecologist, specialised in Maternal Medicine.

With extensive training and expertise, focusing on recurrent miscarriages and pregnancy complications, Professor Shehata is dedicated to delivering the highest standard of care to our patients. His passion for improving reproductive health and his commitment to excellence have shaped the values and principles that define CRP Clinic.

Miscarriages can occur at any stage of pregnancy and leave couples feeling overwhelmed and heartbroken. If you have experienced two or more consecutive pregnancy losses, known as recurrent miscarriages, we recognise the unique challenges you face.

Our team offers comprehensive testing and personalised treatment plans tailored to your specific needs. Our goal is to identify the root causes behind recurrent miscarriages and develop a customised approach to optimise your chances of a successful pregnancy.


Lymphocytes, such as B cells, T cells, and Natural Killer (NK) cells, are vital components of the immune system that safeguard the body against infections and diseases. Imbalances in NK cell activity during pregnancy can lead to complications, recurrent miscarriages and repeated failed implantation following in vitro fertilisation (IVF).

Overactive immune factors like antinuclear antibodies (ANA) and thyroid antibodies, such as thyroid peroxidase (TPO) thyroid thyroglobulin antibodies (TTG) and thyroid stimulating hormone receptor antibodies (TSH-RAB), have also been associated with an increased risk of miscarriage, indicating a potential role of an overactive immune system in pregnancy loss.
Hormonal imbalances can present challenges for couples trying to conceive and increase the likelihood of miscarriages.

Polycystic Ovary Syndrome (PCOS) is a condition that can hinder successful pregnancies. Studies have revealed a link between PCOS and recurrent miscarriages, potentially attributed to factors like insulin resistance, elevated insulin levels, and heightened androgen levels often observed in PCOS.

Thyroid problems can also elevate the risk of miscarriage. Although the precise mechanisms are not fully understood, thyroid hormones are crucial for the development of various bodily tissues. Abnormal thyroid hormone levels can negatively impact fertility and pregnancy outcomes.
The womb, or uterus, serves as the nurturing environment for fetal growth and development during pregnancy. A healthy womb environment is essential for a successful pregnancy.

Issues related to the neck or structure of the uterus can contribute to pregnancy loss mainly in the second trimester after 14 weeks gestation.

Cervical incompetence refers to a weakened cervix that may struggle to support the growing fetus as the pregnancy progresses. This condition can affect women who have experienced late miscarriages or premature deliveries. Additionally, invasive treatments of the cervix for abnormal smear tests can increase the risk.

Womb malformations are another potential cause of miscarriage. These congenital conditions can vary in type and severity, including uterus didelphys, unicornuate uterus, bicornuate uterus (heart-shaped), and septate uterus. It remains unclear whether these malformations directly cause recurrent miscarriages and surgical interventions to correct them must be carefully considered.

Polyps and fibroids, non-cancerous growths in the womb could lead to failed implantation and, rarely, miscarriages. In some cases, surgical removal of fibroids may be necessary.
Although rare, infections can have serious consequences, including miscarriages.

Bacterial Vaginosis (BV) has been associated with late miscarriages, premature deliveries, and post-delivery womb infections. BV occurs due to a disruption in the normal vaginal bacteria balance and is the most common cause of vaginal discharge among women of childbearing age.

Symptoms of BV may include thin white or grey discharge, a distinct fishy odour that intensifies after intercourse, genital area itching or irritation, and a burning sensation during urination. Diagnosis confirmation typically involves a vaginal swab and antibiotics are prescribed to treat BV once it is confirmed.

Group-B Streptococcus (GBS) is one of the many bacteria that normally live in our bodies and which usually cause no harm. GBS may be passed from person to person through direct physical contact. It is not a sexually transmitted disease. Testing for GBS is not routinely offered to all pregnant women in the UK. There is evidence that group B Strep can cause late miscarriage (death of the baby between 14 and 24 weeks of pregnancy) and stillbirth (death of the baby after 24 weeks of pregnancy up until the baby is born). We don’t understand why group B Strep causes stillbirths or late miscarriages in some babies but not others. However, thankfully stillbirths are relatively uncommon in the UK, and group B Strep is not a common cause of them, accounting for around 1% of all stillbirths before labour in high-income countries. So, it is rare that someone carrying GBS will have a stillbirth or late miscarriage caused by GBS. We’re not aware of any evidence that group B Strep causes earlier miscarriages (before 14 weeks of pregnancy).
While the causes of recurrent miscarriages were historically attributed solely to women, we now understand that male factors can also contribute to pregnancy loss.

High levels of sperm DNA damage have been linked to an increased risk of miscarriage and poorer pregnancy outcomes, whether conception occurs naturally or through assisted reproductive techniques.

At our clinic, we offer a test to assess DNA damage in sperms. Men are advised to ejaculate 2-3 times within the week leading up to the test but abstain from sexual activity for 48 hours before the test. The sperm sample is sent to a laboratory in Copenhagen for analysis, preserved in liquid nitrogen.

Abnormal results from the test usually prompt a consultation with a urologist for further evaluation. Several factors can contribute to high DNA fragmentation, such as excess weight, smoking, infections, elevated temperatures, exposure to heavy metals, chemotherapy, certain medications, and varicocele (enlarged veins in the scrotum). It is crucial to investigate and address these factors to improve sperm health and reduce the risk of miscarriage.

If treatment is recommended, a complimentary repeat test is offered after 3 to 6 months to assess the impact of the intervention on sperm integrity. To ensure availability, we advise scheduling the appointment in advance.
This condition is a placental lesion associated with recurrent pregnancy loss at any stage of pregnancy. The pathology report does not always mention CHI as a possible pathology and may include other names which more or less represent the same thing. These include Chronic (histiocytic) intervillositis of unknown etiology (CIUE), Massive Chronic Intervillositis, Nonspecific Chronic Macrophagic Intervillositis, Histiocytic Intervillositis, Chronic Villitis or Chronic Villitis of unknown etiology (CVUE)

Autoimmune or allergic phenomena were identified and treatment include immune therapy of different kinds and for different durations. The diagnosis is a histopathology one and include idiopathic inflammatory lesion, intervillous space location, extensive maternal infiltration of inflammatory mononuclear cells (monocytes, lymphocytes, histiocytes) in particular CD68, intervillous fibrinoid deposits and trophoblast erosions of varying degree, diffuse (massive) or multifocal infiltration.

We understand that experiencing a miscarriage can be a lonely and isolating journey, we want you to know that you are not alone. Our caring and supportive team is here to provide you with the empathy, understanding, and expertise you need to navigate through this challenging time.

If you or a loved one has experienced recurrent miscarriages and are seeking compassionate care and support, we encourage you to reach out to us. Our dedicated team of specialists is available at both locations to provide comprehensive care tailored to your needs.

We offer extensive investigations and treatments for subfertility, addressing both male and female factors. Our range of fertility treatments includes advanced techniques such as in vitro fertilisation (IVF) and intrauterine insemination (IUI) to increase your chances of achieving a successful pregnancy.

As a satellite clinic to Kings Fertility, we ensure that our patients receive the highest standard of care and access to cutting-edge fertility technologies.

Treatments We Offer

Superovulation is a fertility treatment option for women with ovulation disorders, irregular menstrual cycles, or infrequent release of eggs. This technique involves using medications, such as Letrozole, to stimulate the ovaries and promote the growth of follicles. Our clinic success rate average is 10% per cycle with best results in the first 4 cycles. The process includes:
  1. Follicle Stimulation: Medications are administered to stimulate the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which help the ovaries produce more follicles. This medication is typically taken for a few days during the menstrual cycle.

  2. Ultrasound Assessment: Regular ultrasound monitoring is conducted to assess the size and number of follicles and adjust the medication dosage accordingly. The ultrasound scans also help determine the timing of ovulation triggers.

  3. Ovulation Induction: An injection of human chorionic gonadotropin (HCG) is given to trigger ovulation and the release of mature eggs.

  4. Timed Intercourse: Based on the ovulation trigger injection, timed intercourse is planned to optimise the chances of conception.
Intrauterine insemination (IUI) is a fertility treatment where prepared sperm is directly inserted into the uterus during the woman’s fertile window, increasing the chances of conception. This procedure is recommended for couples with issues such as low sperm count, motility problems, or cervical mucus abnormalities, as well as unexplained infertility. The process includes the steps above for superovulation in addition to the following steps:
  1. Sperm Preparation: The male partner provides a semen sample, which is processed to isolate the healthiest and most viable sperm.

  2. Insemination: Using a small catheter, the prepared sperm is gently inserted into the uterus, optimising the chances of fertilisation.

  3. Post-Procedure: After the IUI procedure, the woman can resume normal activities immediately.

  4. For couples where the male partner has high sperm DNA fragmentation, we offer an advanced technique called microfluidic separation (Zymot). Zymot is a sperm selection device that isolates sperm with the least amount of DNA damage, potentially increasing the chances of successful pregnancy in eligible couples.
IVF is a highly effective fertility treatment that involves combining eggs and sperm in a laboratory to create embryos. The resulting embryos are then transferred to the uterus for implantation and development. IVF is recommended for couples with blocked or damaged fallopian tubes, sperm-related issues, or unexplained subfertility.

The IVF procedure includes:
  1. Ovarian Stimulation: The woman receives hormone medications to stimulate the ovaries and produces multiple eggs. Blood tests and ultrasound scans are conducted to monitor follicle development and ensure the eggs are collected at the optimal time.

  2. Egg Retrieval: The eggs are collected using a guided needle aspiration procedure performed at our partner clinic, Kings Fertility.

  3. Fertilisation: The collected eggs are fertilised with prepared sperm in a laboratory dish. If fertilisation is successful, embryos start to develop and are monitored for two to five days. Embryos can also be cryopreserved (frozen) for future use.

  4. Embryo Transfer: A selected number of embryos are transferred to the uterus using a special catheter guided by ultrasound. This step is performed at our partner clinic, Kings Fertility.

  5. Pregnancy Test: Approximately two weeks after the embryo transfer, a pregnancy test is performed to confirm the success of the treatment.

Your fertility journey is not one you have to face alone. Our team is dedicated to providing ongoing support, guidance, and counselling throughout the entire process.

We are committed to being by your side, offering reassurance, answering your questions, and celebrating your milestones as you move closer to realising your dream of starting or growing your family.

At CRP Clinic, we understand the importance of comprehensive care and support during pregnancy, especially when it comes to monitoring the health and development of your baby.

Our Fetal Medicine team utilises advanced ultrasound technology to provide a range of specialised scans and assessments to ensure the well-being of your baby. From early pregnancy to the third trimester, we offer a variety of fetal medicine services tailored to meet your specific needs.

Services We Offer

The nuchal scan is a crucial scan conducted between 11 and 13 weeks of pregnancy. It serves multiple purposes, including accurately dating the pregnancy, assessing the baby’s anatomy, and providing a risk assessment for Down’s syndrome and other chromosomal abnormalities. Additionally, it helps calculate the risk of developing high blood pressure during pregnancy (pre-eclampsia).
During the third trimester, growth scans are conducted to monitor the baby’s growth rate and identify any potential concerns. These scans also help detect issues related to amniotic fluid levels and blood flow to the fetus, ensuring the optimal development and health of your baby.
During the third trimester, growth scans are conducted to monitor the baby’s growth rate and identify any potential concerns. These scans also help detect issues related to amniotic fluid levels and blood flow to the fetus, ensuring the optimal development and health of your baby.
Cervical length scans involve a safe and non-painful procedure that measures the length of the cervix using a transducer inserted into the vagina. These scans are used to assess the risk of preterm labour by checking for signs of shortening or dilation. If the cervix is found to be shorter than expected, our team may recommend monitoring or treatments to help prevent preterm delivery.
Experience the joy of seeing your baby in remarkable detail with our 3D and 4D high-definition ultrasound scans. These scans provide a three-dimensional reconstruction of your baby’s face and body, allowing for a unique bonding experience and providing reassurance during your pregnancy journey.
NIPT analyses cell free DNA in maternal blood and gives a strong indication of whether the fetus is at high or low risk of having Trisomy 21 (Down’s Syndrome), Trisomy 18 (Edwards Syndrome) or Trisomy 13 (Patau Syndrome).

The test identifies 99%, but not all, of the fetuses with Trisomy 21, 97% of fetuses with Trisomy 18 and 92% of fetuses with Trisomy 13. The NIPT test can be performed in women carrying one or two alive fetuses at any stage in their pregnancy from 10 to 32 weeks.

The results from the test will generally be available within one weeks and we will notify you as soon as we receive them by phone and email/letter. In about 5% of cases the test does not give a result. This is due to technical problems with the analysis of the sample and does not suggest that there is a problem with the baby. If you want you can have the test repeated (at no cost) and there is a 50% chance that the test will give a result.

If the NIPT test shows that there is a high risk that the fetus has Trisomy 21 or 18 or 13 it does not mean that the fetus definitely has one of these defects. If you want to be certain if the fetus has one of these defects you should have CVS or amniocentesis. If the NIPT test shows that there is a low risk (less than 1 in 10,000) that the fetus has Trisomy 21 or 18 or 13 it is unlikely that the fetus has one of these defects.

The NIPT test does not provide information on physical defects, such as heart or brain abnormalities and spina bifida, or fetal growth. It is therefore advisable that you still have nuchal ultrasound scans at 11-13 weeks and at 20-22 weeks to examine the fetal anatomy and at 32-36 weeks to examine the fetal growth.

Our Fetal Medicine team is committed to providing you with exceptional care throughout your pregnancy. We combine advanced technology, expertise, and compassionate support to ensure the best possible outcomes for you and your baby.

Contact us today to schedule an appointment and let us be a part of your prenatal care journey.

At the CRP clinic, we understand the importance of proactive gynaecological care for women’s health and well-being.

Whether you’re seeking a routine check-up, a fertility assessment, or a private menopause clinic, our experienced team is here to provide personalised and routine care tailored to your needs.

Check-Ups and Assessments

Regular well-woman check-ups are vital for maintaining optimal gynaecological health. Our comprehensive Wellwoman check-up is designed to assess your overall health and detect any potential issues at an early stage.

During this annual visit, our skilled and friendly gynaecologists will review your medical history, perform a thorough physical examination, including a pelvic ultrasound, and conduct relevant tests such as blood work. This comprehensive assessment allows us to identify any risks or concerns and provide appropriate preventive or diagnostic measures.
If you’re planning to start a family or have concerns about your fertility, our fertility check-up and assessment can provide valuable insights into your reproductive health. Our experienced gynaecologists will conduct a thorough evaluation, including a detailed medical history, physical examination, and pelvic ultrasound to assess the health of your reproductive organs.

Hormonal tests and screenings for sexually transmitted diseases may also be recommended to gather a comprehensive understanding of your fertility potential. With this information, we can offer guidance, discuss any concerns, and explore potential treatment options if necessary.
The menopausal transition can bring about a range of symptoms that may impact your quality of life. At our private menopause clinic, we have a dedicated team of gynaecologists who specialise in menopause management.

We offer a variety of treatment options to alleviate menopausal symptoms, such as hot flushes, mood swings, and vaginal dryness. Hormonal replacement therapy (HRT) is one effective treatment that can help manage these symptoms and reduce the risk of associated conditions like osteoporosis and heart disease. Our expert gynaecologists will work closely with you to develop an individualised treatment plan that addresses your specific needs and concerns.
Our Endometriosis clinic was designed to provide comprehensive and specialised care for individuals affected by this challenging condition.

Endometriosis occurs when tissue similar to the lining of the uterus grows outside the womb, leading to symptoms such as pelvic pain, heavy menstrual bleeding, and fertility issues.

At our clinic, we offer a range of services aimed at effectively managing endometriosis and improving your quality of life. Our team of gynaecologists conducts thorough assessments to diagnose your condition and develop a personalised treatment plan tailored to your unique needs.

Treatment options may include medication to improve symptoms, hormonal therapy to regulate hormone levels, minimally invasive surgery to remove endometrial tissue, and fertility preservation strategies for those planning to conceive.

Advanced Gynaecological Scans

Gynaecological scans are important diagnostic tools used to assess the health of the female reproductive system. These scans provide detailed images of the uterus, ovaries, and surrounding structures, helping gynaecologists identify abnormalities, diagnose conditions, and plan appropriate treatments.
Our 3D scanning technology offers enhanced imaging capabilities, providing three-dimensional views of the pelvic organs. This advanced imaging modality allows for more detailed visualization of anatomical structures, facilitating accurate diagnosis of gynaecological conditions such as fibroids, cysts, and uterine abnormalities. With our 3D scans, we can provide comprehensive assessments and personalized treatment plans tailored to your specific needs.
Saline infusion sonography, or saline scan, is a specialized procedure used to evaluate the uterine cavity. During this exam, sterile saline solution is infused into the uterus, allowing for clear visualization of the uterine lining and any abnormalities present.

Saline scans are particularly useful for detecting conditions such as polyps, fibroids, and uterine adhesions, which may contribute to infertility or recurrent miscarriages. By identifying these issues, we can develop targeted treatment strategies to address your gynaecological concerns and optimize your reproductive health.
HyFosy, or Hysterosalpingo-Foam Sonography, is a minimally invasive procedure used to assess tubal patency, or the openness of the fallopian tubes. This innovative technique combines ultrasound imaging with the injection of a sterile foam solution into the uterus, allowing for real-time visualisation of the fallopian tubes.

HyFosy is an effective method for evaluating tubal health and identifying blockages or abnormalities that may affect fertility. By confirming tubal patency, we can help determine the most appropriate fertility treatment options for you, whether it be natural conception or assisted reproductive techniques.

Surgical Procedures

Hysteroscopy is a procedure that allows our gynaecologists to examine the inside of the uterus using a thin, flexible instrument called a hysteroscope. By inserting this instrument through the vagina and cervix into the uterus, we gain a clear view of the uterine cavity, enabling us to identify and address any abnormalities.

Hysteroscopy is particularly valuable for diagnosing and managing conditions such as uterine polyps, fibroids, adhesions (Asherman’s syndrome), and abnormal uterine bleeding. During the procedure, therapeutic interventions can be performed as necessary, including the removal of polyps, excision of adhesions, or endometrial biopsies for further evaluation. The procedure can be done under local anaesthesia, although we typically recommend sedation to enhance patient comfort during the process.
MVA is a suction procedure that is used to remove the pregnancy tissue after a miscarriage from the womb while you are awake or under sedation. MVA is a very safe procedure. However, there are risks you need to consider before you agree to the procedure (details will be explained and discussed). After the procedure vaginal bleeding can last up to 14 days but should gradually stop, like a period and period-type cramp pain for 24 – 48 hours.

At our women's health clinic, we offer a full range of services to support your overall wellbeing, fertility, and gynaecological health. Our highly skilled team provides wellwoman checkups, advanced gynaecological scans, and minor surgical procedures with a focus on attentive and personalised care.

We provide high-quality specialised care and support to promote men’s health and well-being. Our urologist specialises in men’s health, focusing on male fertility and overall well-being. We offer comprehensive assessments and tailored treatment plans to address male infertility concerns. Similar to our approach to women’s health, we also provide annual Wellman checks to proactively monitor men’s health and detect any potential issues.

Check-Ups and Assessments

Understanding male fertility is crucial for couples trying to conceive. Our fertility evaluations go beyond traditional semen analysis to assess the quality and health of sperm. We consider factors such as sperm count, motility, morphology, and DNA integrity, which can impact the chances of conception and pregnancy.

Through advanced diagnostic techniques, we can identify potential causes of fertility issues and offer personalised treatment options. Lifestyle modifications, targeted therapies, and assisted reproductive techniques like IUI or IVF may be recommended based on individual needs and circumstances.
Regular check-ups are essential for maintaining optimal health. Our Wellman check-ups are designed to evaluate overall health and identify potential risk factors or underlying conditions early on.

During the visit, our experienced urologists conduct a thorough medical assessment, including a comprehensive medical history review. Vital signs, such as blood pressure, height, and weight, are measured.

We also offer a detailed testicular examination and, if necessary, a testicular ultrasound to assess testicular health. Additional blood tests, including PSA (Prostate-Specific Antigen), liver and kidney function tests, male and thyroid hormonal tests, full blood count, and diabetes screening, may be recommended to provide a comprehensive health assessment. A urine analysis may also be included as part of the evaluation process.
Testosterone is the male hormone responsible for changes during puberty and also is important for healthy sperm production and a man’s sex drive and well being. Symptoms of a low testosterone include a reduced sex drive or less strong erections. More subtle symptoms include a lack of energy, strength or endurance, loss of height, decreased “enjoyment of life”, tiredness, reduction in work performance and ability to play sports. Testosterone levels can be affected by lifestyle factors.

Testosterone replacement is not recommended when a couple are planning to have children due to the negative impact on sperm production but alternative medication may be available that boosts the body’s own testosterone levels and the quality of sperm.
Lifestyle, stress, medications, age and conditions such as diabetes can all have an impact on the ability to achieve and maintain an erection. It is not unusual for men to first notice such problems related to stressful periods in their lives. With appropriate investigation and exclusion of serious medical problems most men can improve their situation with the various treatments that are now available.
Rarely men can suffer with difficulty ejaculating and may be related to diabetes or rarely testicular cancer but specific advice, medical treatments or assisted reproductive techniques can be used to overcome this problem. Premature ejaculation can also respond to counselling but if unsuccessful prescribed medication may be effective.
Rarely men can suffer with difficulty ejaculating and may be related to diabetes or rarely testicular cancer but specific advice, medical treatments or assisted reproductive techniques can be used to overcome this problem. Premature ejaculation can also respond to counselling but if unsuccessful prescribed medication may be effective.
Reduced flow, frequent visits to the toilet and waking at night to pass urine are problems that can have a significant impact on a man’s quality of life. There is now greater awareness by men of the prostate and issues that may affect it. The prostate anatomically sits below the bladder and at the junction point of the tubes that transport sperm and urine.

Prostate cancer is very rare under the age of 50 but men with a strong family history or Afro-Caribbean origins may be more at risk. More commonly the prostate enlarges for benign reasons but the symptoms this cause can have a significant effect on quality of life. Infectious problems such as prostatitis can also give similar symptoms more commonly in younger men.

Appropriate and prolonged antibiotic treatment may be required but consideration of effects of infection and antibiotics on sperm production must also be considered.

At the Wellman Clinic, we are committed to providing high-quality care and support to promote men's health and well-being.

Our team of experts combines their skills and knowledge with a compassionate approach to ensure that each patient receives personalised attention and effective treatment options. By addressing male health concerns, including fertility issues and general well-being, we aim to empower men to take control of their health and lead fulfilling lives.

Pioneering approach
to fertility challenges

We promote cutting edge scientific medical approach to diagnose and treat miscarriages and failed IVF attempts.

High Success Rate

Our experienced team of specialists has achieved excellent success rates, with over 80% of our patients experiencing successful pregnancies following our tailored treatment plans.

Personalised care

Each patient we see is unique and we provide tailored strategies to address their specific circumstances and family planning goals.

Compassionate support

We understand that experiencing a miscarriage can be a lonely and isolating journey. We want you to know that you are not alone. Our caring and supportive team is here to provide you with the empathy, understanding, and expertise you need to navigate through this challenging time.

Holistic Care for Couples'
Health and Fertility

We understand the importance of addressing both men's and women's concerns when it comes to starting a family. We provide tailored Wellwoman & Wellman services along with thorough fertility screening and complementary therapies. Our aim is to support and improve overall health as couples embark on their journey to parenthood.

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